Yes. You will need to configure your graphic's card for multiple displays. Also, in your graphic's card control panel there should be a place to set preview for secondary device as fullscreen or theatre mode depending on card manufacturer.
Setting in MSP7 that applies to MSP8 too.
When applying filters and viewing them as fullscreen you need to click on the monitor with wrench button under preview window. Preview Playback Option dialog will open and you need to change External playback device to Dual Head Device.