I have used changing profile in Bibble 5 quite often. For majority of my shots served Wedding profile well, and in too contrasty situations portrait had provided good starting point. I miss look profilez too. Unfortunately, there was major problem with the Kodak colormanagement engine which causes a lot of headache to me and many others demanding users. It was causing nasty posterization in shadows. There was a lot of noise on the forums and IMO the good name of Bibble was hurt a lot, as the problem lingered so long. According to developers it was unsolvable with Kodak CME. So I am really willing to sacrifice the look profiles for much better shadows. Though, developers had somehow mitigated that problem onsome cameras -on D7000 raws I have discovered that pushing blacks slider to negative values will actually move them out of the problematic area, the posterization dissaper. Then you only need to move blackpoint triangle on curves tool to the right, for increasing contrast. Unfortunately this workaround does not work for my D300 images.
Only the change of colour engine in ASP finally solve this problem for all users of different cameras. So, do miss lookprofiles, but I am happy that now the shadows rendering is perfect.