Do you have any idea what the format is? Where did the file come from?
You can try converting the file to something else with SUPER
(FREE!!!). SUPER has lots of format options, so if you're making a regular DVD you can choose DVD-compatible MPEG-2 with LPCM or AC3 audio. If you need help with the format details, let us know what kind of disc your tring to burn (DVD, Blu-Ray, NTSC or PAL, etc.
(And if you download SUPER, follow the confusing links on their confusing website and make you're downloading SUPER, and not another program from one of the advertisements!)